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In-depth analysis of important topics in neuroscience

Research image of green and purple mouse brain slices.

Putting a bright idea to the test

A surprising wave of findings in mice suggests that light and sound flickering at 40 hertz clears the brain of Alzheimer’s-disease-linked plaques. Several companies are hoping to prove it works in people.

By Shaena Montanari
21 August 2024 | 11 min read
an illustration of scientists parachuting

The perils of parachute research

Scientists who study autism in lower-income countries are working to end practices that exploit or ignore collaborators and communities on the ground.

By Linda Nordling
6 June 2024 | 11 min read
Illustration of a series of squares containing distinct patterns.

Can an emerging field called ‘neural systems understanding’ explain the brain?

This mashup of neuroscience, artificial intelligence and even linguistics and philosophy of mind aims to crack the deep question of what "understanding" is, however un-brain-like its models may be.

By George Musser
5 June 2024 | 21 min listen
Close-up of a green glass slide embedded with dozens of tiny electrodes.
Neurobiology Microphone

Making cancer nervous

Nerve cells in the brain and throughout the body can turbocharge tumor growth — a finding that not only expands conventional ideas about the nervous system but points to novel therapeutic targets for a range of malignancies.

By Sarah DeWeerdt
13 November 2023 | 24 min listen
Photograph of a gloved hand pointing to a computer screen that is displaying an image of a mouse brain.
Interneurons Microphone

Uncertainty and excitement surround one company’s cell therapy for epilepsy

After 10 years of work, Neurona may have the data to quiet its skeptics. But its ongoing clinical trial will be the ultimate test.

By Angie Voyles Askham
5 October 2023 | 19 min listen
Research video of a zebrafish larva (zoomed in on the gut) being given glucose.

On the periphery: Thinking ‘outside the brain’ offers new ideas about autism

Neuronal alterations outside the brain may help to explain a host of the condition’s characteristic traits, including sensory changes, gut problems and motor differences.

By Sarah DeWeerdt
13 April 2023 | 20 min read
Coraline with her family at home in Pennsylvania.

The promise of telehealth in autism diagnoses

The COVID-19 pandemic forced a reckoning, in which autism clinicians had to redefine best practices and expand how children are evaluated. The remote assessments they developed may help solve a persistent problem: the long wait families endure to get a diagnosis in the United States.

By Lydia Denworth
15 February 2023 | 22 min read
Three groups of people meet and mix at a crossroads.
Spectrum Microphone

Autism research at the crossroads

The power struggle between researchers, autistic self-advocates and parents is threatening progress across the field.

By Brady Huggett
25 January 2023 | 30 min listen
Large graphic numerals 40 in black on white.

40 under 40

In 2022, we asked our profile subjects and sources to flag rising stars in their labs or among their former students. The result is this list of 40 young researchers who are working on autism-related science across the globe.

By Spectrum
22 December 2022 | 5 min read
A transplanted human organoid labeled with a fluorescent protein in a section of the rat brain.
Spectrum Microphone

Hot topics in autism research in 2022

This year saw the debut of ever-more complex techniques to grow and analyze brain organoids and other 3D tissue cultures, among other advances.

By Spectrum
22 December 2022 | 7 min listen

Explore more from The Transmitter

Young researcher sitting in the grass holding a pillow shaped like a fish.

Seeing research through a new lens: Q&A with Pei Yuan Zhang

When she’s not in the lab, the cognitive scientist films documentaries that challenge her love of data and order.

By Olivia Gieger
20 September 2024 | 7 min read
Illustration of children looking at a gigantic set of building blocks, some of which display genetic sequences on their surfaces.

Autism is more heritable in boys than in girls

If boys have greater inherited liability for autism, the female protective effect may not fully explain the sex difference in prevalence.

Illustration of a brain.

This paper changed my life – ‘Response of hippocampal synapses to natural stimulation patterns,’ by Dobrunz and Stevens

The work demonstrated how to effectively combine controlled in-vitro experiments and the messiness of natural brain patterns.

By Robert Froemke
17 September 2024 | 4 min read